Research
From molecular modelling to validated therapeutics.
We work across the full drug-discovery pipeline — designing candidates in silico, synthesising them at the bench, and validating them against priority pathogens.
Areas of Focus
Five complementary research streams.
Computational Medicinal Chemistry
Molecular modelling, virtual screening, structure-based drug design and ADME-Tox prediction to prioritise therapeutic candidates before bench work.
Organic & Synthetic Chemistry
Targeted synthesis of sulphonamides, triazoles, chalcones, pyrazoles and quaternary ammonium salts with anti-infective profiles.
Anti-infectives Research
Antimalarial, antitubercular and antimicrobial drug discovery against ESKAPE pathogens and resistant strains.
Cheminformatics & Network Pharmacology
Building chemical databases and network-pharmacology models for African medicinal plants and phytochemical products.
Ecotoxicology of Pharmaceuticals
Risk assessment of antibiotic residues in hospital effluents across the Volta Region of Ghana.
Publications
Recent Output
- Published
Adzah B. Y., Amengor C. D. K., et al.
Dual-Targeting Sulfamethoxazole derivatives Inhibit Quorum Sensing and Efflux Pumps in ESKAPE Pathogens: Integrated Computational Design and Antimicrobial Validation.
- Published
Osei M., Amengor C. D. K., et al.
Synthesis of 1,2,3-triazoles by click chemistry and exploring their antimalarial properties: An antimicrobial and computational study.
- Manuscript submitted
Vuvor F., Amengor C. D. K., et al.
Synthesis of optimised sulphonamides with antimicrobial activity.
- In progress
Gyan P., Amengor C. D. K., et al.
Synthesis of quaternary ammonium salts with anti-infective properties: An antimicrobial and computational study.